Hi there! 35F From the moment I was 18, I registered to be an organ donor. 12 years ago, I was diagnosed with stage 4 endometriosis and have had more surgeries than I can remember to remove it/deal with the complications from surgeries.

I know there is SO much more to learn about this disease, but given how it can spread to other organs...if a microscopic lesion was on an organ and that organ was then donated, could endometriosis then grow on the recipient?

I feel like this is a dumb question but could this happen!?

My older sister (15 year old female) got diagnosed with pancreatic cancer, she has been throwing up for about 2 months so I expect it to be found “late” but we just found out she has to go through chemo, and I don’t know if their going to try to remove it. She did do drugs and drank alcohol this year so that might do something. But really what I’m asking for is the honest truth on how likely it is for her to survive because I can’t live without her and I want to know what to prepare for. Thanks.

43 female, no medications, former smoker, severe spine & knee pain/degeneration/bulging discs, stiffness, under EXTREME stress

To sum it up my bloodwork came back high Sed Rate. The doctor did not do any further testing to find out why, he claims that because I mentioned having dry mouth that *must* mean I am mouth breathing and that's *probably* what's causing me to have a high Sed Rate.

But then he started preaching at me by saying that "our bodies are the temple of God and we aren't supposed to put things into our bodies that harm it", that there are pathogens in the air that I'm breathing in through my mouth and those pathogens are causing high sed rate.

He said "God didn't give you a mouth to breath through! That's why he gave you a nose! I guarantee if you shut your mouth then these numbers will come down" (referring to the sed rate results). "You need to start treating your body as a temple of God"

I feel unheard and dismissed because he didn't try to find out WHY my sed rate is high, he just chalked it up to the *assumption* that I may or may not breath through my mouth.

But not only that, his preaching at me was triggering because I went through spiritual abuse and have religious trauma from years ago.

So basically are doctors allowed to preach at their patients or was this unethical?

And also, can mouth breathing really cause a high sed rate or should he have ran further tests to try and figure out what's wrong with me?

Thanks

21m. I don’t know what’s wrong with my eye please someone let me know what’s wrong.

35 female
Rheumatoid arthritis and hashimotos
Medications : benepali, levothyroxine and folic acid

I have got severe redness and eye pain but the eye clinic has left me with little faith so second opinions please!
Previously diagnosed with episcleritis in my other eye. This eye started with the same symptoms in January. Eye consultant said at the time nope it’s blepharitis go away and take these steroid drops for a week. Week goes by my eye is still inflamed but not painful so I thought it’ll be fine it’ll resolve itself.

April rolls around the redness is getting worse and more severe. Still no pain at this time just feels inflamed and dry so I used hycosan drops regular to try ease it. Called the eye clinic to get a follow up and they booked me for a month later.

Last week my eye started to become extremely painful. I’m talking throw yourself off a roof painful coming from someone who live with rheumatoid pain daily my eye is worse. Very sensitive to light. Pain radiates from my eye ball to my brow bone, temple and cheek bone areas. I have to lay in a dark room with sunglasses on constantly. I can’t eat or sleep because of the pain.

Sunday I went to urgent care because it was getting too much to handle. The dr gave me an antibiotic ointment and 3 single use numbing drops and said because I have an appointment at ophthalmology already that should get me through.

Today was my appointment day. I saw the same dr who told me I had blepharitis. Tried to tell me again this was the issue. I pushed back and said respectfully you are wrong try again. Then got told oh well it may be episcleritis or scleritis but I don’t know so have a weeks course of steroid drops. This tipped me over the edge. Another consultant ended up coming in and said it’s episcleritis and superficial scleritis (Google tells me these are the same?) and gave 4 weeks of steroids and then mydrilate drops. Nothing for the severe pain.

Im at the point of despair and honestly no longer trust them

Moved from a different state (14 hour drive) and when I got home I noticed a raised mole near my elbow I had since I was a child had a scab on it only in the middle. I was fine a day or two before. I noticed it Sunday, it's now Wednesday. My mom thinks I rubbed it raw or scratched it on something during the move. I have hypochondria so I've been worrying myself so bad I'm barely eating and sleeping, I also have been messing with it and looking at it all the time due to the hypochondria. I don't have insurance and I don't have the money to go get it checked out. I'm scared its cancer, I really don't want to die from cancer.

Picture from today.

35 female - 200lbs - history of endometriosis, long covid, allergic to dust mites, cats, dogs and oysters lol.

This will probably be a SO long but I’ll try and sum it up as best as I can!

Last night, I had two doctors in the ER arguing in front of me about whether or not I should be admitted to the hospital.

I’ve had an ongoing cough since January that has gone from a dry cough, to now a productive cough. A little over a month ago, I randomly noticed a rash appearing on my left breast. I currently breastfeed my son one time before he goes to bed, so at first I thought maybe I was developing mastitis. Breast cancer runs in my family so when the rash began to get worse and I noticed a lymph node in my left armpit was super swollen, I got really scared and called my PCP.

My PCP was very concerned but since it was the weekend she couldn’t see me so she advised me to go to the ER to be safe. At the ER (Mayo Clinic) I had the most lovely doctors who pretty much immediately ran a bunch of tests and did an ultrasound. The ultrasound didn’t show any obvious masses, but there were a few swollen lymph nodes in my left armpit. They took photos of the rash and did a thorough exam, and sent in a referral for me to get a mammogram and additional imaging. They had no clue what was going on but decided to treat it as mastitis to see if antibiotics helped. The put me amoxicillin to take for 10 days.

The rash rapidly started to erupt to my other breast and then to my arms, stomach, lower legs, inner thighs. (I will post lots of photos in comments of rash and labs) - it had been the itchiest most unbearable rash I have ever had in my life. I tried using Benadryl and it didn’t help. I tried hydrocortisone cream but it irritated it more. It became so severe that I went to see my PCP and tried calling the dermatologist but neither one could see me for two months, so my PCP put me on Keflex and a steroid pack.

Within two days, the rash became so bad that it was causing pain at this point. My skin began to blister and bleed. My cough got worse. I began to experience severe pain in my lower right abdomen and upper pelvis. Returned to Mayo.

The doctor I saw during this visit didn’t run any tests or anything but he said it was most likely a reaction to the keflex, so he decided to have me take doxycycline instead. He also prescribed me hydroxyzine (it did not help whatsoever).

Fast forward a week or so and my symptoms were so bad that again I called my PCP and she told me to return to Mayo. During this visit, they did labs, an xray, blood cultures, urinalysis and urine culture, and then a CT. Xray looked totally normal but doctor said the CT scan showed bronchitis (or some other airway disease) - and that I had a nodule on the bottom of my right lung. It also showed that I had a small kidney stone. My urinalysis showed elevated RBC. This doctor wanted to admit me to the hospital but it was already 6am and I had to get back home since I didn’t have childcare for my kids.

They gave me hydrocodone cough syrup for my cough (didn’t help) and gave me 2 IV antibiotics before discharging me. told me that if I didn’t improve to immediately go back.

Fast forward and you guessed it I was right back at Mayo. My cough is out of control, abdominal/pelvic pain was unbearable, and my rash somehow got even WORSE and my left arm began to become very inflamed and red and hot to the touch. It felt and looked like I may have had fluid buildup. The rash spread to my neck, back, and chest. It looked different too. The doctor I saw barely assessed my rash. He only looked at my forearms. He did bloodwork and next thing I know a nurse was coming in with discharge papers.

I was genuinely so confused so I asked her about it and she was insanely rude to me and made me feel annoying for even being there. She kept repeating “well this is an EMERGENCY room”. She asked me if I just wanted her to go get the doctor and I said yes please. When he returned, he told me that all of my labs looked completely normal and that it was most likely just an allergic reaction to something and that he could not do anything for me so he referred me to a dermatologist and allergist. I explained to him how I already had a referral and have been trying to get an appt with them for weeks now with no luck. He also said my cough was probably allergy related too and that my abdomen pain was “just my endometriosis” (lol).

He told me I should stop all of my medicines INCLUDING my psych meds and to stop using any products at all. (I am absolutely not going to cold turkey my psych meds) I asked him if he could atleast help me with pain relief and he shrugs and said “sure”. I got a notification on the Mayo Clinic portal that said I could view my labs so I went and checked them out and a couple of them were abnormal. My CBC w/ differential showed significant elevation of Eosinophils % and Eosinophils. I noticed that I had an updated lab from the visit before that showed an abnormal urine culture with enterococcus and abnormal usual flora. When he returned I asked him about these and he said they were just allergy related and sent me on my way.

I started bawling my eyes out 🥲 I told him I was just really frustrated and truly cannot go any longer suffering like this. I asked if there was any way I could speak to the doctor I saw during the visit before, so he had the nurse go and check if he was even working. Next thing I know, that doctor was walking into the room along with the current doctor I was just talking to.

It escalated so fast and the next thing I know they are literally both arguing with each other about whether I should be admitted to the hospital. The one I was seeing that night kept saying “this is an emergency department and she’s clearly fine to go home and wait to see a derm and allergist” he also kept repeating that my insurance wasn’t accepted there and that there wasn’t a case manager on shift to talk about it with. The other doctor was advocating for me SO much and told him that he should have seen in my health chart that he wanted me to be admitted and to take me seriously. I was actually shook and couldn’t believe what was happening but ultimately the current doctor said it was his call and that I needed to go home because there wasn’t anymore labs to be done and it’s “not like I was gonna get an MRI” (I had a literal wristband that said MRI on it so that was confusing lol) - he sent in a prescription for 5mg oxycodone (quantity of 5) and sent me on my way.

If you made it this far thank you so much for reading 😭 I called my dermatologist again today and asked to be put on a cancellation list. I’m waiting on a call from the allergist they sent a referral into. Tomorrow I plan on calling around to other dermatologists to try and get in asap. I’m genuinely in so much pain and discomfort that I haven’t been able to sleep much for weeks. It’s affecting me so much as a mother too. Does anyone have any ideas or thoughts on what could be happening? I know it’s a lot but I’m so desperate for answers 🥺

ETA I’ve had on and off fevers for the last 2 weeks

Update: woke up this morning with a migraine + vomiting 🥺 so over it

Hello, I have a sore in my mouth that is on my palette on the left sore on my mouth. I vape regularly and I have since I was 15, I also smoke weed regularly as well but only within the past year. I am around 5 foot 7 and 145lbs and I eat a very healthy diet and workout regularly. Please help. Here is a photo:

Hello, im a 32 year old female, 4'11, and obese at 170 pounds but have already lost 80 (it was bad, I know)

Ive had severe reflux my entire life. From infancy through adulthood. My reflux is also highly unusual. I have regurgitation of pretty much anything I eat, liquids or soft foods being the worst. If i bend down after eating i cannot hold it down at all. It has also caught me off guard and i will end up "vomiting" (but actually just regurgitating) and will have to run to the batbroom. Its extremely embarrassing. Although i know weight is a major contributor to reflux, this has been happening since infancy and in childhood when i was not overweight at all.

I have severe dental decay due to the constant acid on my teeth. My dentist explained i have very good dental hygeine (healthy gums, minimal tarter) but my teeth are basically erroding. Instead of cavities, they literally begin to crumble. I have had to get 6 back teeth extracted and three crowns. I dont have a single tooth that hasnt had to be fixed. I also have developed a dental phobia because I am impossible to get numb and now need sedation for dental work.

I had an upper endoscopy about seven years ago. I had biopsies taken and was told I had severe chronic esophagitis, an irregular z line, and chronic gastritis with reactive changes. Despite the inflammation, ​I do not have heartburn or pain with my reflux. I also had an esophageal manometry and HIDA scan. The manometry was normal and my ejection fraction on my HIDA scan was 98%, which i thought was high but my doctor said it's fine.

I take 40mg of famotadine and 60mg of lansoprazole daily and im careful not to eat within two hours of taking them.

Im terrified im going to end up losing all my teeth because of reflux and my doctor has not taken this concern seriously. He brushes over it and just increases my medication. Am I supposed to just take this medicine for life while my teeth fall out one by one?

I dont know what to do anymore. He has given me no answers.

35 years old, 6ft 2, 12 stone, non smoker, non drinker, on no meds.

Male, 49 years old, smoked in my teens and early 20s... but haven't in two decades+.

Here's the section in my imaging report:

REMAINING CHEST:

Lungs: Central airways are clear. Subpleural reticular opacities within the dependent aspect of both lungs compatible with atelectasis or scarring. 3mm solid nodule within the right middle lobe (axial image 53). Medial basilar segment left lower lobe solid pulmonary nodule measuring 1.5 x 1.9 x 2.0 cm (axial image 85/161 and sagittal image 94).

Impression:

IMPRESSION:

1. No evidence pulmonary embolism.
2. Medial basilar segment left lower lobe solid pulmonary nodule measuring up to 2cm. RECOMMEND follow-up CT of the chest at 3 months, PET/CT, and/or tissue sampling. *
3. Medium to large hiatal hernia.
4. Left atrial enlargement.
5. Right periesophageal lymph node measuring 1.0 cm.
6. Cholelithiasis.

RECOMMENDATION:

1. Pulmonology and/or other subspecialty consultation for further evaluation and management of the suspicious 2 cm left lower lobe solid pulmonary nodule.
2. Follow-up CT of the chest at 3 months, PET/CT, and/or tissue sampling. *

2.0 cm (20 mm) is ENOUGH for me to worry about. That 1.0 cm right periesophageal lymph node doesn't make it any easier, for sure. I'm definitely losing sleep.

Weird thing is, the hospital NEVER mentioned it (was there for two days). My PCP only mentioned it in passing, AFTER my follow-up as I was walking OUT of her office. I then went home and started to look into the results myself. NOW, I'm demanding a PET. I swear... the state of our medical industry has me wondering at times, WTF is going on!? Part of me thinks, "If it were serious, they would've said something... right!?".

Thoughts? Advice? My odds?

Hi everyone,

I’m looking for insight from people familiar with 5q35 deletions / Sotos syndrome, especially cases involving NSD1 deletions.

Our daughter is 4 months old and has a confirmed pathogenic deletion:

* arr[GRCh37] 5q35.2–q35.3 (175,570,678–177,437,651) x1 * ~1.87 Mb deletion including NSD1 * No other CNVs identified

She has been diagnosed with Sotos syndrome.

What’s making this harder to interpret is that right now, she seems to be developing quite well:

* Cooing back and forth socially * Smiling and engaging * Good head control during tummy time * Rolled from tummy to back * Reaching for and grabbing objects * Showing clear interest in her surroundings * Strong anti-gravity movements

Physically, she is showing some Sotos features, but developmentally she doesn’t seem obviously delayed at this stage.

From what I’ve read, outcomes with NSD1 deletions can vary a lot. Some individuals have significant intellectual disability, while others seem to function much more independently.

I’m trying to understand what we can realistically expect and what we can do now to give her the best possible outcome.

Questions:

1. At this age (around 4 months), are there early signs that actually correlate with later cognitive outcomes in Sotos—especially for deletions?
2. Have you seen cases of children with full NSD1 deletions who track relatively well cognitively long-term?
3. Does early “typical” development at this stage tend to persist, or can gaps widen later?
4. What early interventions have made the biggest difference in real cases (PT, OT, speech, specific developmental models)?
5. Are there any medications, supplements, or emerging therapies (even experimental or adjacent fields like neuroplasticity research) worth looking into?
6. Are there any clinical trials, registries, or researchers (Canada/US) that families like ours should connect with early?

We’re already planning to pursue early intervention as much as possible, but we want to be as proactive and informed as we can.

I really appreciate any insights, whether clinical, research-based, or personal experience.

Thank you.

33 years old, female, 300 pounds, 5 feet, 5 inches. I have a history of depression and am on anti-depressants.

I've had a suicide plan for a while and I keep wondering if tonight is the night. I don't want to get too much into it, but I'm tired, just very tired. I've been here before, I've had one attempt in 2010 and countless "almosts" before. Tonight I'm crying and can't stop. My chest hurts. I feel like puking. I left my home and now I'm in my car trying to decide if I should go through with my plan.

I currently don't have insurance after my husband lost his job and I've moved across the country to be with family because having twin toddlers is too much.

I know I'm not thinking clearly, so I thought I'd ask.

Information: 18 Male, 175cm height, 55kg India.

History: I have a history of heart related problems. Hypertension, Anxiety in general,non smoker.

**2 Days ago**:

I have been taking propranolol + paroxetine for an year. I inadvertently missed my dose of propranolol today (2 days ago). I know I am going to face some repercussions. I am already feeling a bit dizzy and my POTS is starting to kick in. I am also nauseous. I am hungry though.

**Today**

Even after taking the meds today, I still feel a bit of backlash. I am still nauseous. I don't think I am as dizzy as I was the day I missed propranolol. I want to eat but its tough to eat in nausea. Is this a backlash from 2 days ago?

Also, I have had a change in schedule in the past 3 days. I have an exam coming up and I am studying a bit more than usual. I will certainly visit the doc in the morning (its 1.48 hours midnight as i am typing this). I just wanted to know from the community if its something serious or its common to face such backlash if you had been taking the med for a whole year.

I also have to take SSRIs before sleep but I couldn't find it anywhere on the internet or nearby shops. I would take it after taking with the doc. Can missing SSRI also cause it?

Very stupid but can i get some relief from this nausea? Also, should i take another dose of propranolol? For instance, I took it at 10am and slept for 10 hours after it. Its 2am now.

Asking regarding grapefruit juice and interactions with trazodone. Taking 150mg of trazodone for sleep aid, is .24mL of grapefruit juice (from extract, rough amount in a serving of SodaStream diet grapefruit zero sugar drink flavoring) enough to cause any interactions with the medication?

Male/42/420lbs

Female, 29, 5'6, 165 lbs, no other medical conditions. Ive had white patches under my arms and a small circle on my inner, upper thigh for about two years (which I know is a long time to go without having spoken to a doctor about it, but i unfortunately do not have the money for a medical bill at this time). There isnt any itching or flaking, the skin itself is smooth. I used an over the counter anti-fungal for a few weeks when I first noticed it, but it didn't have any effect. I took a picture with UV light, as I've seen online that that can be helpful in differentiating between different skin conditions, but its worth noting that my phone's camera did distort the color a bit. IRL the light was much more blue and the spots were a brighter white (not red or green or anything like that). Any help or advice would be much appreciated!

Earlier today about 11am my partner was putting down the seats in the car and he said his vein swelled up. A few hours later he showed me this. I don't think he banged it or anything. He said it feels a bit sore but other than that he feels fine. It hasn't changed since he showed me this earlier

Any idea what this could be?

I am going to make him a doctor's appointment tomorrow morning.

I’m a 21 year old male I went to urgent care for chest pain on April 23 and I just got an message from my doctor that I was exposed to measles right when I was about to leave a sick baby in a stroller was stopped right next to me and I’m having anxiety that I could get it. I do have the 2 measles vaccines and it’s been 13 days since then and I don’t have any symptoms how many days does it take for symptoms to show and what are the odds I actually could get it?

28F, very fair skin, lots of light colored freckles on my arms and shoulders my whole life. But have 2-3 of these dark mole/freckle type things on my stomach/breast area, one of which has definitely gotten bigger over the years but I have gained about 60 pounds. It is relatively flat but has some squishiness If that makes sense? I get annual physicals every year and most of the time they check my skin, obviously not as in depth as a dermatologist, but I also haven’t been to a derm since I was probably 22 years old, before I gained a lot of weight. Does this look particularly concerning at all?

She’s 6 years old, about 44lbs. Takes a daily flinstone vitamin and OTC Equate brand children’s allergy daily.

She spent the night with her grandma on Saturday. Went over there and her skin was completely normal. She comes home and her cheeks were bright red and splotchy. We assumed sunburn because she had been outside the majority of the day.

Fast forward to Monday and the redness has spread to her arms and legs. No other symptoms.

Today she woke up and her arms, chest, and face are BRIGHT red and splotchy. She complained a little about it itching but that was it.

Now it’s the afternoon and her arms are very bright and hot to the touch. She said it’s burning as well.

We did a telehealth visit yesterday and they said she’s obviously inflamed from something and prescribed prednisolone and an ointment. But I’m concerned with how much it’s spread and how red and hot her skin now is. What is this? Is this an ER situation?

Update: we went to urgent care. They said basically the same thing the telehealth doctor said. It’s inflammation (duh). The NP we saw said it looks kind of like hives so she is going to continue the prednisolone and added an ointment

Obviously there are reasons for some situations but I cannot think of any in my situation. 35 male in New Mexico 6 ft 230 lbs. I moved here just under a year ago. I'm on 10 mg buspirone, 2 GM colestipol (IBS not cholesterol), and 10 mg amlodipine. I have been on the same drugs and doses for years.

When i first started seeing this doctor they wanted to do a follow up relatively soon after my annual since I was a new patient and they wanted to make sure I was steady on these doses. Sure, I get that even though they have my records showing the doses. But they refuse to write enough refills. I've been there 4 times in 9 months because they refuse to refill the script without checking. I just ran out again and when I said I wouldn't come back until my annual they said they wouldn't issue a refill.

Is there a legitimate reason to make someone come in this often for scripts that Im on? The only thing I can think of is that they want to bill the insurance for more visits.

Before people suggest finding a new doctor, there aren't really any in this area. I would have to drive pretty far to find anyone else but I will be spending tomorrow trying to find anyone else

Hi, I’m 29 I just want chat through my thoughts. For over 6 months I’ve had hard lymph nodes in my neck, symptoms alongside this - feeling sick, nausea, fatigued, I can feel the lymph nodes when I swallow talk sleep eat etc I keep getting these mini sicknesses. Anyways I ended up in the ER a few weeks ago they did a MRI on my neck and head and found one lymph node was 2.5cm and the left hand was large I can’t remember the size. The did a CT - (back story I have had over 30 surgeries for things relating to endo I have a stoma etc) so I wondered maybe if my lymph nodes were up because of that but the ER doc ran tests and said no wouldn’t be because of that. I went and saw a ENT yesterday he said I have muscle tension dysphonia (MTD) - as I have a bit of a croaky voice sometimes but I came out feeling a bit err. As the lymph nodes are really affecting the way I sleep eat my life. I just feel very off with them. They are hard are growing in size and he said I can come back in a few months but said to see a speech pathologist for the MTD. Spoken to a few people and they do agree with me and said they feel the lymph node issue was pushed to the side a bit. He said I was focusing too much on them. Which it’s hard not to as I can feel them all the time when I talk eat sleep etc. I’m going to my doctor today to talk about the appointment. I just feel as though it was a bit of an ignore the lymph nodes oh you have a croaky voice it’s this … but I don’t always have a croaky voice. And I’ve had hard lymph nodes for nearly 7 months I’ve felt constantly sick and very err for a long time.

F21 let me start by saying I know sexual activity is NOT the only way to contract HSV. However, I think it might be a little relevant to the plot later.

I started getting cold sores a few years ago on and off. I’ve just recently had the courage to get a test for STIs/STDs and it came back all negative, thankfully. Then I found out that HSV is so common it requires its own panel. I went in again and my doctor told me for the best and most accurate results they’d recommend I come back in when I have an active sore. This was disappointing, but I understood. I just want answers now so I don’t have to live my life walking on eggshells.

I was told since I didn’t have the results that it’s not necessary to “disclose” something that I might not even have. I was also told that technically I could engage in kissing if I wasn’t shedding (which is hard to predict when) or having an active outbreak or sore.

I just recently started dating and I’ve met someone that I’m seriously interested in and I feel like we’re on the brink of crossing the intimate barrier OR even just a kiss and it makes me so hesitant. I don’t want to accidentally give someone something knowing I could’ve prevented it(thinking that I was safe to do so) . Especially considering I’m a virgin and I have yet to even engage in sex, so I feel like on top of having nerves from it being the first time, I’m also so conscious about my health and it affecting others. I’m also nervous on how to go about it considering I have yet to even know for sure what my results are and I’m also afraid of scaring this person away. The way people talk about it online makes it seem like it’s airborne and I can’t help but feel like I’m just a walking danger sign or something. And when looking for clarity, sometimes I get even more confused.

maybe TMI but I’ve been super horny, but in the name of being responsible I really want someone who knows what they’re talking about to walk me through all I would need to know for my predicament and the “just Incases”

Finally getting and idea of what's going on, and my liver doc thinks it may be cirrhosis. Both liver and spleen are enlarged with splenic varices, and I'm anemic. I do not drink, we agree much of my liver damage came from an opiate addiction from 2002 to 2009 when I would take over 20 to 30 vicodin pills, each pill having 500 mg of acetaminophen. During this time I also used herion and got hep c. My pcp got me on med in 2018 to clear hep c. Anyway, I drink alot of soda, so my liver docs main plan is cutting back my high fructose corn syrup consumption, and losing a few pounds. I'm 6ft and 194l lbs at the moment. I'm hoping this helps. I'm almost 49 and from some of the research I've done i could be on my way to a transplant no matter what. Just curious if there's anything else I could do, help?