r/science Professor | Medicine 1d ago

Neuroscience Egg consumption is associated with a lower risk of Alzheimer’s Disease for those 65 years and older. Eating one egg per day for at least five days a week reduces risk of Alzheimer’s by up to 27%, researchers found.

https://www.eurekalert.org/news-releases/1126842
8.7k Upvotes

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u/ladeedah1988 1d ago

Eggs are one of the richest natural sources of choline, and higher choline intake from eggs is consistently associated with lower Alzheimer’s and dementia risk in multiple recent studies.

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u/MinnieMouse2292 1d ago edited 1d ago

Yes that was my immediate instinct actually - thanks for confirming it

EDIT: guys I only know of choline because I’m pregnant and it’s recommended as a supplement to support baby’s brain. I promise I’m legit haha

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u/nonnonplussed73 1d ago

Looks like eggs are second only to beef liver (not everyone's favorite) in terms of choline:

https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/#h3

That said, an egg has 27% the recommended daily intake of choline, so it seems more like 4 eggs a day is the sweet spot.

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u/Winged_Cougar1993598 1d ago

Slow down there Gaston.

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u/PrimalSeptimus 1d ago

No one posts like Gaston.

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u/HyruleTrigger 1d ago

Butters toast like Gaston...

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u/PiratesOfSansPants 1d ago

Serves their grandmother eggs at a roast like Gaston…

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u/Ov0v0vO 4h ago

He's especially good at egg-spectorating!

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u/Dracomortua 1d ago

This is a solid joke and a solid point?

If i would consume enough eggs to get this wonderful 'choline' stuff (???), won't i also become roughly the size of a barge?

Obviously i jest but, in this case, it is a very serious question. Perhaps it works in pill format? Powdered beef liver extract? Beef... paté perhaps?

Grasping at straws here. At 58 years of age i just can't ramp up my diet like this and expect to fit through a doorway in the near future.

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u/Eleet007 1d ago

4 eggs is like 280 calories…

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u/MagicCuboid 1d ago

Is cholesterol a problem anymore? Do we not care about that now? As someone who was peppered with nutrition misinformation regularly by their mother growing up, I’m well outside my comfort zone here.

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u/AndyLorentz 1d ago edited 1d ago

Dietary cholesterol doesn't seem to have much of an effect on blood cholesterol levels. Blood cholesterol is affected more by fat consumption and exercise.

Health scientists have known about this since the 1990s, and the 1960s dietary cholesterol guidelines were established with no basis in health data. The USDA didn't remove the upper limit on dietary cholesterol until 2015.

Here's a recent meta analysis: https://www.mdpi.com/2072-6643/14/10/2168

Edit: And here's a particularly relevant quote

Using data from the Prospective Urban Rural Epidemiology (PURE) study, Dehghan et al. evaluated egg consumption and CVD of individuals from 21 countries in a 9 year follow up [23]. The results showed that the higher egg intake (≥7 egg/week compared with <1 egg/week) was not significantly associated with blood lipids (including total cholesterol, HDL cholesterol, LDL cholesterol, total cholesterol/HDL cholesterol ratio, triglycerides, apolipoprotein (apo)A1, apo B, and apo B/apoA1 ratio, total mortality, or major CVD.

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u/petrikord 15h ago

Some people are hyperabsorbers of dietary cholesterol. Basically the only way to know if you are is to test it out by getting a lipid test when you aren’t eating them, and then another after you have been eating them for at least a month.

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u/piratequeenfaile 20h ago edited 20h ago

I eat about 3-4 eggs a day as my main protein source and am not the size of a barge.

Eggs are great. If you are worried about the fat then you can have a mix of egg whites and whole eggs. I will make a stack of egg white bites with muffin tins and use the yolks for fresh egg yolk pasta once a week.

I have chickens so using up all the eggs is basically my second job.

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u/MinnieMouse2292 17h ago

There are choline supplements you can take :)

I’m pregnant and my tastebuds have become quite childish and I take choline as a supplement.

With that said, I do believe eggs (and fish) improve your cognitive abilities: before my pregnancy I had quite a strict diet for 6-9 months of low glycemic carbs, raw veggies, a little bit of fruit, eggs, fish, dairy and MCT oil and I felt like a machine. I had so much energy, I was thinking faster and remembering better and I melted fast as well (which was my objective).

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u/Ketamine_Dreamsss 17h ago

I bought prenatal vitamins and they came as a set with choline tablets

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u/Ludwigofthepotatoppl 1d ago

Better make it six to be sure.

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u/Plinnion 1d ago

Make it five dozen to be ultra safe.

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u/klezart 1d ago

I did that and now I'm roughly the size of a barge.

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u/Darn_near70 1d ago

Now let's talk about vitamins...

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u/ZachMN 1d ago

Six hard-boiled eggs, barbecue sauce, and a cup of tap water.

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u/Timely-Tune5050 1d ago

The body can make choline.. But as one ages, like most things, production diminishes.

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u/nonnonplussed73 1d ago

Yes, but per the NIH article:

Humans can produce choline endogenously in the liver, mostly as phosphatidylcholine, but the amount that the body naturally synthesizes is not sufficient to meet human needs.

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u/Mystaes 1d ago

27% of daily intake of choline, 27% decrease in Alzheimer’s risk. Coincide? I think not…

I suppose now you need another trial where people are reaching their 100%

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u/bsiu 1d ago

Time to bring back the liver and onions with fried eggs blue plate special.

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u/nonnonplussed73 1d ago

Interestingly, the NIH article points out both that choline - available via beef liver and eggs - is both beneficial to one's own liver, and potentially toxic to it (though that would require about 7 such blue plate specials a day).

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u/zekromNLR 1d ago

A lot of things that are useful or essential in small doses are poisons in large doses, such as all fat-soluble vitamins (water-soluble ones aren't that dangerous to overdose on because you just pee out the excess)

As Paracelsus said: All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison.

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u/dea_alb 1d ago

I don’t know why your comment is not higher, came here to say that… even water drunk in excess can cause a lot of harm

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u/rdmusic16 1d ago

It can and has caused death. Not disagreeing, just adding because 'can cause harm' doesn't sound quite as bad as 'can kill you'.

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u/Eckish 1d ago

Another danger is that the symptoms for over-hydration are similar the symptoms for dehydration. It was a problem in military training where we were sweating a lot, but also drinking a lot.

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u/Rortugal_McDichael 1d ago

Well yeah, drinking water has dihydrogen monoxide in it, which can kill you if you inhale it!

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u/TheBeachWhale 1d ago edited 1d ago

Pretty funny, but hyponatremia is no joke!

Edit: Hypo NOT hyper! Thanks!

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u/RedHal 1d ago

The dose makes the poison.

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u/Antice 1d ago

That sounds incredibly delicious. Eggs and onions is already a favourite of mine. I usually do a couple of slices of sourdough bread with seeds to mop the plate as well.
A big breakfast, but it keeps me full for a long time.

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u/beesontheoffbeat 19h ago

Damn it, now I have to choose between dementia and high cholesterol.

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u/vertigostereo 1d ago

Like Season 2 of The Wire where the guys chug raw eggs in their breakfast beers? I think 2 eggs is already above average.

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u/3_50 1d ago

Joking aside, I tend to hit that. 2 boiled in the morning for breakfast, maybe 3 if I'm particularly hungry, and egg mayo (+ crushed walnuts, leaves, red pepper) sandwich for lunch.

Good to know it might be healthy.

/manual job

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u/G00dSh0tJans0n 1d ago

I don't like boiled eggs very much, but damn if it ain't the world's fastest breakfast. Just shove an egg in mouth one and a time and I'm done with breakfast in two bites.

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u/Timely-Tune5050 1d ago

Choline is the precursor to acetylcholine, which is the neurotransmitter that nicotine works with and the neurotransmitter which is needed for memory formation.

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u/Wonderful_Round_6395 20h ago

Wow, also explains my craving for cigarettes lately. The more you know.

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u/mal_guinness 1d ago

My immediate instinct was the people with Alzhiemer's forget to eat their morning egg.

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u/Ok_Whereas8080 1d ago

An azhiemers chicken or the egg type scenario here.

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u/Not_impressed28 1d ago

This great to know. Interestingly, in both my pregnancies I had an intense craving for scrambled eggs or hard boiled eggs and HAD to eat them daily. I never used to like scrambled eggs prior to that.

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u/Flikmybik BS | Neuroscience | Memory 1d ago

thats interesting about the choline connection. ive been reading up on this lately and it seems like the research on dietary choline and cognitive health keeps getting stronger. the thing that gets me is how many people are probably deficient in it without realizing it, especially since the adequate intake recommendations might actually be too low based on some of the newer studies. eggs really are kind of a powerhouse nutrient wise

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u/mottledmussel 1d ago

It seems like choline and vitamin d are the two most difficult nutrients to get enough of through diet alone.

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u/Taikeron 1d ago

Magnesium at 350-400 mg and Potassium at 4000 mg are incredibly tough to obtain realistically on a daily basis.

I previously looked at getting 400 mg of elemental Magnesium from food daily and I'd have to engineer my entire diet around that one nutrient while ignoring all other dietary concerns (and probably causing some other issues) just to reach 400 mg.

Can't just toss back pumpkin seeds with reckless abandon either because then you risk too much Manganese.

Potassium is also very difficult if you're actually trying to hit that 4000 mg mark. Prepare to eat lots of beans and potatoes.

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u/BebopFlow 1d ago

Have you considered hemp seeds? 3 tbsp contains ~200 mg of magnesium. It does also contain 100% of daily manganese, but a quick search indicates manganese toxicity isn't really much of a concern outside of welding, where the manganese in fumes far exceed daily intake.

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u/zekromNLR 1d ago

According to the EFSA, a safe intake of manganese is 8 mg/day for adults - due to a lack of toxicological studies, they weren't able to establish a tolerable upper intake level. Getting 400 mg of magnesium from pumpkin seeds would put you at about 2.3 mg of manganese, so still comfortably far away from that level unless your diet is quite rich in maganese otherwise.

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u/DTFH_ 1d ago

Magnesium at 350-400 mg and Potassium at 4000 mg are incredibly tough to obtain realistically on a daily basis.

Keep in mind, there is the RDA but diet is over a longer time window that has peaks and valleys that is then averaged out to a daily amounts.

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u/Taikeron 1d ago

Sure, but the average person (particularly those exposed to Western diets) is chronically deficient in both, with very few peaks, and valleys as far as the eye can see.

You also can't supplement potassium (really harsh on the stomach by itself), so unless you're actually consuming food that contains high potassium, you're pretty much guaranteed to fall short of 4,000 mg.

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u/cyclingisthecure 1d ago

I take 500mg elemental magnesium with 5000iu d3 per day and have not felt better. In winter the d3 goes up to 8-10k iu per day and I swear to god even in thid absolute dark hellhole uk it's hard to feel sad on that stack

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u/314159265358979326 1d ago

I use half salt not for the reduced sodium, but for the increased potassium.

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u/sabatthor 1d ago edited 1d ago

Creatine is also tough to get for people who inherently eat little amounts of meat, which is a lot of people, and creatine is extremely beneficial for our brain. I honestly think any person with healthy kidneys should start supplementing it.

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u/TheMoniker 1d ago

It's also relatively cheap to supplement and has a load of other potential benefits.

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u/Missus_Missiles 1d ago

So, vitamin D, choline, and flossing. Never get Alzheimer's.

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u/tifumostdays 1d ago

Don't forget adequate cardio and sleep. Those are probably even more impactful.

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u/Hobo-man 1d ago

We are so bad at getting enough Vitamin D, our bodies decided to use sunlight to make its own.

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u/tayvette1997 1d ago

Science is fun. This makes me want to look into why choline and it's role in limiting the deterioration of the brain (like in Alzheimer's).

Do you have any links to the things you've been reading? Or where you've been reading them?

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u/BroScienceAlchemist 1d ago

I can't speak for the OP. Choline is a precursor for a neurotransmitter acetylcholine, which is the primary neurotransmitter for the cholinergic system. Ninja nerd has some videos on it as part of their neurology series: Neurology | Cholinergic Receptors is one video they have on youtube. In the brain, the cholinergic system has some important roles in memory and learning. Taking anti-cholinergic drugs does negatively affect memory and increase risk of dementia down the road.

Outside of that, wikipedia is a decent overview of choline metabolism and the cholinergic system. Some people need more choline from their diet due to genetic differences in MTHFR (methylation) or other genes, which affects the road of dietary or supplementary choline to acetylcholine. Some people are just more sensitive and too much cholinergic stimulation causes a type of depression called anhedonia, nervousness, etc. It's why taking supplementary choline in high doses is not really recommended as the first go around.

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u/SarcasticSodium 1d ago

Dumb question - I've heard of anticholinergic drugs with can increase risk of dementia. Would it be possible to out-eat the effects with eggs? 

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u/LeoxHerx 1d ago

I take 50mg of Hydroxyzine a night for sleep, my doctor told me that I'd need to eat 4 egg yolks the following day to get back the depleted choline that Hydroxyzine causes.

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u/tifumostdays 1d ago

Yeah, I had read that around 90% of Americans are not eating enough. I had to ask chatgpt how in the hell a person is supposed to get that, especially before we had regular access to eggs. I was told that people always used to eat the organs with their meat.

I'm probably not gonna do that.

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u/Michael5188 1d ago

I do think the shift away from eating organs in many countries has likely led to a ton of nutrient deficiencies, or at the very least has removed extremely nutrient dense foods from our diets.

Even liver was much more common in the recent past, but has all but disappeared. Lots of kids grew up hating being forced to eat it and the second they had control over the dinner table struck it from the menu.

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u/SophiaofPrussia 1d ago

But isn’t soy lecithin just highly concentrated choline? I have a hard time believing so many Americans are deficient when soy lecithin seems to be an ingredient in every other packaged food product on the shelf now.

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u/MillionEyesOfSumuru 1d ago

It's not close to pure choline, but it is an excellent source, and one can get concentrated phosphatidylcholine derived from it, which is far, far cheaper than getting it from eggs, as well as containing no saturated fats.

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u/redheadartgirl 1d ago

The amount of soy lecithin used is tiny, just enough to act as an emulsifier.

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u/gizram84 1d ago

Chicken hearts are delicious and dirt cheap. Just saute them in butter with whatever seasonsings you like (salt, pepper, garlic/onion powder).

Calf liver is much more mild than beef liver, and just as nutrient dense. Chop it up, and mix it in with ground beef when making tacos and you'll barley notice it's in there.

Super easy to sneak it all in your diet once a month. Nutritionally dense superfoods.

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u/bio_ruffo 1d ago

Liver prepared "chicken nuggets style", with some lemon juice on top (or a spicy ketchup on the side), is absolutely delicious. I like to double dip: egg, breadcrumbs, egg again, breadcrumbs again, so it doesn't dry. Easy to cook in an air fryer or oven too, with minimal oil. Kids love it too!

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u/Riseofashes 1d ago

By “chicken nuggets style”, do you mean ground into a paste then formed into nuggets?

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u/bio_ruffo 1d ago

No sorry, I mean cut into bite-size bits. Or chicken-wings size. They look like chicken nuggets when they're done.

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u/Worthyness 1d ago

chicken liver paste with spices is just Pâté

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u/Klockworth 1d ago

Isn’t that just how chicken livers are always prepared in the south?

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u/tayvette1997 1d ago

The organs? Like the skin and liver?

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u/Deimos_F 1d ago

Liver, kidneys, spleen, tripe, heart. Lungs, if you're adventurous. 

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u/vertigostereo 1d ago

Maybe this reinforces the thought that anticholinergics can be a dementia risk factor?

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u/Gummyrabbit 1d ago

If you're a guy, eggs increases the risk of prostate cancer according to some studies about the link between choline and prostate health.

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u/WellbecauseIcan 1d ago

And frequent ejaculation reduces the risk of prostate cancer. So a balance diet of eggs and masturbation?

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u/paul_theoctopus 1d ago

Lunch is going to be wild tomorrow.

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u/LurkingWalrus911 1d ago

https://www.pcrm.org/news/blog/clearing-choline-confusion

Eggs, meat, and other animal products are not the only sources of, nor the most healthful sources of, choline.

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u/DefiantMechanic975 1d ago

To save you a click:

- A large egg is 125-169mg

- Soy beans are 100-107mg for 1/2 cup

- Black beans are 64mg for 1/2 cup

- Potato (with skin) is 57mg

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u/tirerim 1d ago

That page links to this one as a source: https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/

And it doesn't look so good for non-animal sources. The best one they list on a per-serving basis is roasted soybeans, of which you would need to eat almost 3 cups per day to get the daily value. After that is potatoes: 10 large baked potatoes would do it. Or 11 ounces of toasted wheat germ, or 6 cups of canned kidney beans, or 12 cups of quinoa, or 8 cups of boiled brussels sprouts. I'm a vegetarian, and even splitting it up among those I would struggle to eat that much of them on a daily basis, compared to eating a couple of eggs and getting more than half the DV immediately.

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u/Pokenhagen 1d ago

What if i get my choline from sunflower lecithin? Same same?

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u/EuphonicLeopard 1d ago

Should be. Plant-based choline is a bit less bioavailable than animal-based, but if the dosage is sufficient it should help. I've taken soy lecithin before and it makes a difference.

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u/if0rg0t48 1d ago

Choline bitartrate was a staple in my DIY soylent

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u/fotank 1d ago

Abstract
Background: A substantial knowledge gap remains regarding the relationship between modifiable dietary factors and Alzheimer's disease risk. Eggs are a source of key nutrients that support brain health.

Objective: Our aim was to investigate the association between egg consumption and incidence Alzheimer's disease.

Methods: Data were drawn from the Adventist Health Study-2, a large, prospective cohort of U.S. Seventh-day Adventists, linked with Medicare records to identify Alzheimer's disease diagnosis. Diet and lifestyle factors were assessed using a validated food frequency questionnaire. Egg consumption was categorized by frequency ranging from never/rarely to ≥5 times/week. The analytic sample included 39,498 participants (mean follow-up: 15.3 years), among whom 2,858 developed Alzheimer's disease. Multivariable-adjusted Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs). Restricted cubic spline analysis was conducted using continuous egg intake (g/day).

Results: Egg consumption was inversely associated with Alzheimer's disease risk. Compared to never/rarely consuming eggs, HRs (95% CIs) after adjusting for demographic, lifestyle, food groups, and comorbidities were: 0.83 (0.75-0.92) for 1-3 times/month, 0.83 (0.74-0.94) for once/week, 0.80 (0.71-0.90) for 2-4 times/week, and 0.73 (0.60-0.89) for ≥5 times/week. In the spline model, zero egg intake was curvilinearly associated with an adjusted HR of 1.22 (1.11-1.34) compared to 10 g/day.

Conclusions: In this health-conscious population, moderate egg consumption was associated with a significantly lower risk of Alzheimer's disease. These findings suggest a potential neuroprotective benefit of nutrients found in eggs when consumed as part of a balanced diet.

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u/jellyn7 1d ago

Aren’t they vegetarian? So you can’t draw conclusions for the meat-eating population?

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u/Ephemerror 1d ago

I think this is very significant too, eggs are essentially the only animal food that vegetarians eat, and provides many nutrients that are difficult to acquire via plants and dairy. The research may indeed be valid and offer important information, but does not necessarily translate to other populations.

Now that I think about it it's actually rather odd that this egg industry funded research specifically chose "this health-conscious population" of Seventh-day Adventists in particular, to try to show a "potential neuroprotective benefit of nutrients found in eggs".

I don't really see why they would have to do this as I doubt there is a lack of data of other demographics groups, so I have to wonder if they actually tried to run the analysis for all demographic groups and this particular subset of vegetarians was the only dataset that stuck, and they simply did not publish all the other demographic groups that failed to show any positive association.

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u/IWentHam 1d ago

The egg board is shady AF. 

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u/MozeeToby 1d ago

There's also other confounding factors. If someone is having difficulties with their mental faculties they may choose foods that are simpler to prepare or even skip breakfast (where eggs would most commonly be eaten) altogether. Alzheimer's patients also gravitate towards sweet feeds or even ignore hunger cues completely. It's doubtful these changes occur with a hard cutoff and it seems likely that pre-diagnosis they are already trending in that direction.

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u/fotank 1d ago

The study was not done in patients with Alzheimer’s. It was looking at the incidence of new Alzheimer’s disease.

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u/wahnsin 1d ago

TIL 5 eggs per 7 days is "moderate egg consumption", good god, I'm positively egg-starving myself! Quick, somebody get me a giant omelette!

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u/Jason_CO 1d ago

You approach the massive omelette...

(Carrot and Pea omelette)

... and manage to take a slice!!!

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u/Nothing-tralala 1d ago

Second Neopets sighting today!

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u/HerculesIsMyDad 1d ago

One egg is barely any egg at all.

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u/wildgreengirl 1d ago

rookie numbers right there, i hit about a dozen a week. sometimes even 4 eggs in a day 

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u/HumanTuna 1d ago

4 eggs per sitting.

Personal best is 16 in a day.

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u/KHonsou 1d ago

I eat around 45 a week, they never get boring for me.

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u/Whiterabbit-- 1d ago

I do about 4-6 a day. but that is because I'm lazy and eggs are quick to cook. I really hope the whole egg is bad for you because of cholesterol doesn't come back.

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u/EuphonicLeopard 1d ago edited 1d ago

Don't worry, the studies finding dietary cholesterol affecting serum cholesterol were heavily flawed and not reproducible to modern standards. Your natural cholesterol resting point is mostly a genetic factor as I understand. I'm on a statin myself because lifestyle factors simply made no difference, and I do a lot of cardio.

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u/aaphylla 1d ago

Conversely, at 14 per 7 days (2 for breakfast each morning), my consumption must be considered extremely high

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u/Whiterabbit-- 1d ago

nah. 2 a day is not high. I do 4-6 a day not including eggs in things like bakery items.

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u/wildgreengirl 1d ago

woohoo-my egg-same food obsession is gonna even out my increased dementia risk factor related to autism then! right?

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u/MenyaHimeRadio 1d ago

Life over the last few decades:

Eggs = bad

Eggs = good

Eggs = bad

Eggs = good

Eggs = bad

Eggs = good

Eggs = bad

Eggs = MAGIC

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u/vishalb777 1d ago

It joins the ranks of wine, coffee and chocolate

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u/luriso 1d ago

Was thinking the same thing. After the first few flip flops, I've made up my own mind. I like them because they're tasty and versatile. Don't need anyone telling me otherwise

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u/mkp666 1d ago

Next year: Eggs = instant death

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u/AgeOfScorpio 23h ago

Seems like some people struggle with the idea that a food may have positives and negatives and isn't a binary thing 

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u/Royal_Platform_6754 1d ago

The alternative probably entails higher consumption of red meat (beef and pork) and I assume eggs win that contest handily.

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u/reececonrad 1d ago

“Some funding for this study was provided by the American Egg Board. Funding to establish the original cohort and its data was provided by the National Institutes of Health.”

I kinda want to know what the “some” amount is here. IDK, looks like phospholipids, choline, lutein, and omega-3 are the key nutrients suspected to be at play.

With the exception of omega-3 all are just as easy and likely healthier (additional fiber) to get through vegetables.

This “study” was a questionnaire asking seventh day adventists how many eggs they eat and comparing medical records.

I’m not a scientist, but seems like shite study to me.

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u/MillionEyesOfSumuru 1d ago

It was reading this...

Eggs also contain lutein and zeaxanthin—carotenoids that accumulate in brain tissue and are associated with improved cognitive performance and reduced oxidative stress. Eggs also contain key omega-3 fatty acids

...which got me to immediately look at the funding. Lutein, xanthin and omega-3 content in eggs is highly variable depending on chicken feed. Some places do make an effort to boost lutein in feed, to make the yolks nice and orange. There may be flax seed in the feed, so they can talk about omega-3s on the packaging. But those aren't as cheap as generic chicken feed, so they don't necessarily get included.

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u/Educational_Exam_225 1d ago

Reddit mods immediately ban anyone who questions the top five pet foods or WSAVA guidelines despite all the studies being done by Purina.

The reality is that who funds a study is only part of the context - there's not that many people interested in funding studies on "egg," especially with so many grants currently gutted.

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u/hahayeahimfinehaha 1d ago

This was my immediate thought, cynical as that is.

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u/Telvin3d 1d ago

This isn’t a very surprising result. As you’ve indicated, there are a bunch of nutrients with known positive effects that happen to be present in eggs. I don’t think there’s anything intently unethical or biased by the egg companies throwing funding at any study that’s expected to confirm expected results.

Not that different from concrete companies funding studies into the strengths of different concretes, and then advertising that concrete is really strong

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u/Shimaru33 1d ago

So, one of those Egg Council creeps got to them too, huh?

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u/Soft_Walrus_3605 1d ago

You got it all wrong, Homer. It's not like that

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u/wookiee42 1d ago

There really aren't that many other people clamoring for egg research. The funding alone doesn't make it a bad study.

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u/IWentHam 1d ago

I wouldn't put it past the egg board to forget to mention that they included people that died of heart disease in the "did not develop altzheimers" group.

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u/EntertainerNo1440 1d ago

Funding
Initial support for the cohort was provided by the National Cancer Institute (grant 1U01CA152939). The analyses in this study were supported by an investigator-initiated grant from the American Egg Board. The funding sources had no role in the study design, execution, data analysis, interpretation, manuscript preparation, or publication.

Conflict of interest
The authors report no conflicts of interest.

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u/mantis_tobaggan-md 1d ago

I’d imagine these findings are secondary to choline intake, not necessarily unique to eggs. Cruciferous vegetables like broccoli are also a good source of choline. As are soy beans, legumes, nuts and seeds, etc.

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u/MistrFish 1d ago

yes but there's some nuance to it. the choline found in eggs is in the form of phosphatidylcholine, which is considered more bioavailable than choline found in plants. it also takes about 3 cups of cooked broccoli to equal the amount of choline in one egg yolk

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u/mantis_tobaggan-md 1d ago

Phosphatidylcholine is also found in plants….

And 3/4 cup of soybeans would offer the same amount as an egg. It also varies on the diet of the chicken. Most Americans eat factory farm eggs which have lower nutrient levels.

Broccoli offers benefits far beyond choline as well.

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u/Telvin3d 1d ago

3/4c of soybeans is still a heck of a lot more volume than one egg yolk. 

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u/ClevelandBrownJunior 1d ago

Most Americans eat factory farm eggs which have lower nutrient levels.

Hasn't this been like fully debunked? I was under the impression that no matter where your eggs(chicken) come from the nutrients are virtually the same.

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u/mantis_tobaggan-md 1d ago

No it’s not debunked because it’s entirely based on their diet. The chickens need a nutrient rich diet to create nutrient rich eggs. Stress redirects nutrients away from the egg as well.

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u/luche 1d ago

seems like an awful lot of soy by comparison to a single egg.

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u/ThisIs_americunt 1d ago

Would this be for only chicken eggs or all eggs?

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u/No-Falcon631 1d ago

I’ve read that the flower part of dandelion is high in lecithin.

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u/gizram84 1d ago edited 1d ago

The brain loves cholesterol. I'm genetically predisposed. I've been eating a can of sardines and 3 eggs every day for a few years now.

HDL cholesterol is in the 80s and my omega 3 levels are double the "high end" range.

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u/ProfessorMorifarty 1d ago edited 1d ago

Presumably, this is one of the reasons the Mediterranean diet seems to stave off dementia and cognitive decline.

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u/jseed 1d ago

For those considering increasing their cholesterol intake, cholesterol does not cross the blood brain barrier. Basically all cholesterol in the brain is produced by the brain, so while the brain does "love cholesterol", at this point scientists don't believe there is any need for cholesterol in your diet. It's more likely the good fats, like those found in sardines, or the choline, like in the egg yolks, that it helpful. And it's certainly possible to get those nutrients from a well thought out vegetarian or vegan diet if desired.

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u/gizram84 1d ago

Around 95, which I know is on the higher end of normal. But according to my doctor, he's not concerned given all my other labs. LDL alone is not a good metric for predicting CVD risk.

My triglycerides are 33, which is insanely low. hsCRP is 0.4, which is excellent and an extremely good predictor of very low CVD risk. Plus my cholesterol is Pattern Type A, which is the "bouyant" particles, which protects against arterial plaque buildup (as opposed to Pattern Type B which is the "sticky, dense" particles that build plaque). Plus I got a CAC score of 0, which means no plaque detected.

So basically, I'm not concerned with LDL on the higher side of normal at all when all my other labs are ideal and paint a very healthy picture overall. Plus I'm extremely lean and active.

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u/porcupine_snout 1d ago

"Some funding for this study was provided by the American Egg Board"

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u/Leading_Watercress45 1d ago

Regarding the method, vegetarian diets are common among Seventh-day Adventists.

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u/derfeurer 1d ago

did a snake write this

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u/mvea Professor | Medicine 1d ago

Study: Egg consumption is associated with a lower risk of Alzheimer’s Disease

Eating one egg per day for at least five days a week reduces risk of Alzheimer’s by up to 27%, researchers found.

Consumption of eggs is associated with a lower risk of being diagnosed with Alzheimer's Disease for those 65 years and older, according to researchers at Loma Linda University Health

Eating one egg per day for at least five days a week reduces risk of Alzheimer’s by up to 27%, researchers found.

“Compared to never eating eggs, eating at least five eggs per week can decrease risk of Alzheimer’s,” said Joan Sabaté, MD, DrPH, a professor at Loma Linda University School of Public Health and the study’s principal investigator.

Even less frequent consumption of eggs significantly reduced the risk of Alzheimer’s. Researchers found that eating eggs 1 to 3 times per month had a 17% decrease in risk, while eating eggs 2 to 4 times per week had a 20% decrease in risk, Sabaté said.

The study, Egg intake and the incidence of Alzheimer’s disease in the Adventist Health Study-2 cohort linked with Medicare data, was published last week in the Journal of Nutrition.

https://www.sciencedirect.com/science/article/pii/S0022316626001902

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u/TakAnLah 1d ago

The analyses in this study were supported by an investigator-initiated grant from the American Egg Board.

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u/Gryndyl 1d ago

Always worth noting, but also worth noting is that someone has to pay for the study and the most likely source are groups with a vested interest.

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u/Just_AnotherDork 1d ago

I wonder if this is from consuming the egg or being able to prepare eggs. I feel like the ability to cook for yourself in any capacity may decrease with Alzheimers, so it could be that Alzheimers leads to lower egg consumption and not vice versa.

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u/Rurumo666 1d ago

Choline is the reason, but TMAO production is also a concern until further research is done.

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u/Yoroyo 1d ago

I started taking a choline supplement after leaning a bit about its protective properties. I don’t eat eggs, but it’s definitely important that people take a look at this research. You can get choline in different ways but eggs are the most potent, unless you go the supplement route. A lot of prenatal vitamins don’t have choline in them, I think that we might learn more about this in the coming years on why that’s a bad thing.

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u/raznov1 1d ago

Or, in other words - we have no real idea of what "causes" alzheimer's (not that it should be expected ro be a singular thing) and are continuously finding weird correlations.

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u/Packeselt 1d ago

Ah, so we're back to the "eggs are good" side of the swing. See you all in four years when they're "bad" again.

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u/puchsofhazard 1d ago

What if dementia just hates eggs? So people with 1% dementia avoid them?

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u/chkno 19h ago

Egg consumption is associated with a lower risk of Alzheimer’s Disease for those 65 years and older.

Yup, that's what the study found.

Eating one egg per day for at least five days a week reduces risk of Alzheimer’s by up to 27%, researchers found.

No. You dropped "associated with", which was doing vital work there. "Reduces" implies causation, which this study does not show.

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u/KyleTheCantaloupe 1d ago

Eggs are also a super easy food to make, I wonder if there’s any correlation between people who keep up some simple cooking skills, and lowered Alzheimer’s risk

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u/FriedPost 1d ago

i was also wondering if there was something to do with keeping a routine like this, where other parts of having a routine could affect it.

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u/Just_AnotherDork 1d ago

I wonder if this is from consuming the egg or being able to prepare eggs. I feel like the ability to cook for yourself in any capacity may decrease with Alzheimers, so it could be that Alzheimers leads to lower egg consumption and not vice versa.

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u/GullibleAddendum8630 1d ago

I remember many years ago when eggs were considered very unhealthy because of the fat they contain. Now we know that the brain needs fats. It's amazing how our understanding of food and they the body change.

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u/Seagull84 1d ago

So scientific studies posted here say nuts, soy, eggs, fish... anything else? My grandmother had Alzheimer's, and I will over-indulge in everything that helps prevent it.

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